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perspectives on the application of next generation sequencing to the improvement of Africa's staple food crops

dc.contributor.authorGedil, M.
dc.contributor.authorFerguson, M.
dc.contributor.authorGirma Tessema, G.
dc.contributor.authorGisel, A.
dc.contributor.authorStavolone, L.
dc.contributor.authorRabbi, Ismail Y
dc.date.accessioned2019-12-04T11:04:36Z
dc.date.available2019-12-04T11:04:36Z
dc.date.issued2016-01-14
dc.identifier.citationGedil, M., Ferguson, M., Girma Tessema, G., Gisel, A., Stavolone, L. & Rabbi, I. (2016). Perspectives on the application of next-generation sequencing to the improvement of Africa’s staple food crops. In J.K. Kulski, Next generation sequencing - advances, applications and challenges(287-321). Croatia: Intech
dc.identifier.isbn978-953-51-2240-1
dc.identifier.urihttps://hdl.handle.net/20.500.12478/1465
dc.description.abstractThe persistent challenge of insufficient food, unbalanced nutrition, and deteriorating natural resources in the most vulnerable nations, characterized by fast population growth, calls for utilization of innovative technologies to curb constraints of crop production. Enhancing genetic gain by using a multipronged approach that combines conventional and genomic technologies for the development of stress-tolerant varieties with high yield and nutritional quality is necessary. The advent of next-generation sequencing (NGS) technologies holds the potential to dramatically impact the crop improvement process. NGS enables whole-genome sequencing (WGS) and re-sequencing, transcriptome sequencing, metagenomics, as well as high-throughput genotyping, which can be applied for genome selection (GS). It can also be applied to diversity analysis, genetic and epigenetic characterization of germplasm and pathogen detection, identification, and elimination. High-throughput phenotyping, integrated data management, and decision support tools form the necessary supporting environment for effective utilization of genome sequence information. It is important that these opportunities for mainstreaming innovative breeding strategies, enabled by cutting-edge “Omics” technologies, are seized in Africa; however, several constraints must be addressed before the benefit of NGS can be fully realized. African breeding programs must have access to high-throughput genotyping facilities, capacity in the application of genome selection and marker-assisted breeding must be built and supported by capacity in genomic analysis and bioinformatics. This chapter demonstrates how interventions with NGS-enabled innovative strategies can be applied to increase genetic gain with insights from the Consortium of International Agricultural Research (CGIAR) in general and the International Institute of Tropical Agriculture (IITA) in particular.
dc.format.extent287-321
dc.language.isoen
dc.subjectFood Crops
dc.subjectNutrition
dc.subjectPlant Breeding
dc.subjectNext-Generation Sequencing
dc.subjectGenome Selection
dc.subjectDeveloping Countries
dc.subjectFood Security
dc.subjectBioinformatics
dc.subjectDna
dc.titleperspectives on the application of next generation sequencing to the improvement of Africa's staple food crops
dc.typeBook Chapter
dc.description.versionPeer Review
cg.contributor.crpAgriculture for Nutrition and Health
cg.contributor.crpClimate Change, Agriculture and Food Security
cg.contributor.affiliationInternational Institute of Tropical Agriculture
cg.contributor.affiliationInstitute for Biomedical Technologies, Italy
cg.contributor.affiliationInstitute for Sustainable Plant Protection, Italy
cg.coverage.regionAfrica
cg.coverage.regionWest Africa
cg.coverage.countryNigeria
cg.researchthemeBIOTECH & PLANT BREEDING
cg.researchthemeNUTRITION & HUMAN HEALTH
cg.authorship.typesCGIAR and advanced research institute
cg.iitasubjectFood Security
cg.iitasubjectNutrition
cg.iitasubjectPlant Breeding
cg.iitasubjectPlant Genetic Resources
cg.howpublishedFormally Published
cg.accessibilitystatusOpen Access
local.dspaceid80372
cg.targetaudienceScientists
cg.identifier.doihttps://dx.doi.org/10.5772/61665


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