Post transcriptional silencing of reporter transgenes in tobacco correlates whit DNA methylation

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Date
1994
Author
Ingelbrecht, I.
Houdt, H. van
Montagu, M. van
Depicker, A.
Type
Metadata
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Abstract/Description
Endogenous plant genes or transgenes can be silenced on introduction of homologous gene sequences. Here we document a reporter gene-silencing event in Nicotiana tabacum that has a distinctive combination of features--i.e., (i) silencing occurs by a posttranscriptional process, (ii) silencing correlates with DNA methylation, and (iii) this de novo methylation is not restricted to cytosines located in the symmetrical motifs CG and CXG.
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Permanent link to this item
https://hdl.handle.net/20.500.12478/5633
Digital Object Identifier (DOI)
https://doi.org/10.1073/pnas.91.22.10502
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