• Contact Us
    • Send Feedback
    • Login
    View Item 
    •   Home
    • Journal and Journal Articles
    • Journal and Journal Articles
    • View Item
    •   Home
    • Journal and Journal Articles
    • Journal and Journal Articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    Whole Repository
    CollectionsIssue DateRegionCountryHubAffiliationAuthorsTitlesSubject
    This Sub-collection
    Issue DateRegionCountryHubAffiliationAuthorsTitlesSubject

    My Account

    Login

    Welcome to the International Institute of Tropical Agriculture Research Repository

    What would you like to view today?

    Sequence characteristics of PVY recombinants

    Thumbnail
    View/Open
    S09ArtHuSequenceInthomNodev.pdf (284.7Kb)
    Date
    2009
    Author
    Hu, X.
    Karasev, A.V.
    Brown, C.J.
    Lorenzen, J.H.
    Type
    Journal Article
    Metadata
    Show full item record
    Abstract/Description
    Potato virus Y (PVY) is one of the most economically important plant pathogens. The PVY genome has a high degree of genetic variability and is also subject to recombination. New recombinants have been reported in many countries since the 1980s, but the origin of these recombinant strains and the physical and evolutionary mechanisms driving their emergence are not clear at the moment. The replicase-mediated template-switching model is considered the most likely mechanism for forming new RNA virus recombinants. Two factors, RNA secondary structure (especially stem-loop structures) and AU-rich regions, have been reported to affect recombination in this model. In this study, we investigated the influence of these two factors on PVY recombination from two perspectives: their distribution along the whole genome and differences between regions flanking the recombination junctions (RJs). Based on their distributions, only a few identified RJs in PVY genomes were located in lower negative FORS-D, i.e. having greater secondary-structure potential and higher AU-content regions, but most RJs had more negative FORS-D values upstream and/or higher AU content downstream. Our whole-genome analyses showed that RNA secondary structures and/or AU-rich regions at some sites may have affected PVY recombination, but in general they were not the main forces driving PVY recombination.
    https://dx.doi.org/10.1099/vir.0.014142-0
    Multi standard citation
    Permanent link to this item
    https://hdl.handle.net/20.500.12478/2476
    Digital Object Identifier (DOI)
    https://dx.doi.org/10.1099/vir.0.014142-0
    IITA Subjects
    Plant Diseases; Plant Health
    Agrovoc Terms
    Potato Virus Y (Pvy); Genome; Potyvirus; Rna Viruses
    Regions
    Acp; Asia; Europe; North America; East Asia
    Countries
    United Kingdom; United States; Canada; Germany; Hungary; Slovenia; Poland; Japan; France; Spain
    Journals
    Journal of General Virology
    Collections
    • Journal and Journal Articles5283
    copyright © 2019  IITASpace. All rights reserved.
    IITA | Open Access Repository