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    Using biotechnology to enhance host resistance to aflatoxin contaminiation of corn

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    brown-using-2003.pdf (135.5Kb)
    Date
    2003-12
    Author
    Brown, R.L.
    Zhi-Yuan, C.
    Menkir, A.
    Cleveland, T.E.
    Type
    Journal Article
    Journal Article
    Metadata
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    Abstract/Description
    Host resistance is the most widely explored strategy for eliminating aflatoxin contamination by Aspergillus flavus. Breeding strategies for developing resistant corn germplasm have been enhanced by the development of new screening tools for field inoculation and for laboratory screening. RFLP analysis of corn populations has highlighted the possibility that different resistance traits can be successfully pyramided into agronomically useful germplasm, while proteomics has impacted the identification of proteins associated with resistance (RAPs). The identification of RAPs has also been enhanced by the discovery of near-isogenic corn lines in progeny generated in a West African breeding program. The characterization of genes of the aflatoxin biosynthetic pathway has provided a foundation for a genomics investigation aimed at understanding the biochemical function and genetic regulation of aflatoxin biosynthesis. Successful inhibition of aflatoxin elaboration may require not only the action of antifungal compounds, but of compounds that block biosynthesis of toxins as well.
    https://doi.org/10.5897/AJB2003.000-1107
    Multi standard citation
    Permanent link to this item
    https://hdl.handle.net/20.500.12478/4185
    Digital Object Identifier (DOI)
    https://doi.org/10.5897/AJB2003.000-1107
    IITA Subjects
    Maize
    Agrovoc Terms
    Aflatoxins; Contamination; Corn; Molecular Biology; Biotechnology; Host Resistance
    Regions
    Africa; West Africa
    Collections
    • Journal and Journal Articles5078
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