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dc.contributor.authorTuncel, A.
dc.contributor.authorPan, C.
dc.contributor.authorSprink, T.
dc.contributor.authorWilhelm, R.
dc.contributor.authorBarrangou, R.
dc.contributor.authorLi, L.
dc.contributor.authorShih, P. M.
dc.contributor.authorVarshney, R. K.
dc.contributor.authorTripathi, L.
dc.contributor.authorVan Eck, J.
dc.contributor.authorMandadi, K.
dc.contributor.authorQi, Y.
dc.date.accessioned2023-11-01T13:41:50Z
dc.date.available2023-11-01T13:41:50Z
dc.date.issued2023-10-04
dc.identifier.citationTuncel, A., Pan, C., Sprink, T., Wilhelm, R., Barrangou, R., Li, L., ... & Qi, Y. (2023). Genome-edited foods. Nature Reviews Bioengineering, 1-18.
dc.identifier.issn2731-6092
dc.identifier.urihttps://hdl.handle.net/20.500.12478/8326
dc.description.abstractGenome editing can transform agriculture and shape the future of food by improving crop yields and animal productivity, which in turn can help to achieve food security for the growing world population. CRISPR–Cas-based technologies are powerful gene editing tools that are applied to various food products. In this Review, we discuss the applications of CRISPR–Cas aimed at increasing the nutritional value of crops through macronutrient engineering and biofortification or the reduction of the amount of antinutrients. We examine the role of CRISPR–Cas in improving the flavour of crops and reducing post-harvest losses to increase consumer acceptance and decrease food waste. We also highlight the gene editing of animal food products and probiotics. We summarize the regulations for approval of gene-edited foods worldwide and the progressively evolving public view. Finally, we explore the strategies that can help to enhance the efficiency of genome editing techniques and the acceptance of genome-edited foods in the global market, and extend the technology to low-resource settings.
dc.description.sponsorshipNational Science Foundation
dc.description.sponsorshipNational Institute of Food and Agriculture
dc.description.sponsorshipFoundation for Food & Agriculture Research
dc.description.sponsorshipUnited States Agency for International Development
dc.description.sponsorshipFood Futures Institute of Murdoch University
dc.language.isoen
dc.subjectCRISPR
dc.subjectGenome
dc.subjectFoods
dc.subjectCrops
dc.subjectNutritional
dc.titleGenome-edited foods
dc.typeArticle
cg.contributor.crpAgriculture for Nutrition and Health
cg.contributor.crpRoots, Tubers and Bananas
cg.contributor.affiliationUniversity of Maryland
cg.contributor.affiliationZhejiang University
cg.contributor.affiliationInstitute for Biosafety in Plant Biotechnology
cg.contributor.affiliationNorth Carolina State University
cg.contributor.affiliationCornell University
cg.contributor.affiliationBoyce Thompson Institute for Plant Research
cg.contributor.affiliationUniversity of California
cg.contributor.affiliationLawrence Berkeley National Laboratory
cg.contributor.affiliationJoint BioEnergy Institute
cg.contributor.affiliationMurdoch University
cg.contributor.affiliationInternational Institute of Tropical Agriculture
cg.contributor.affiliationTexas A&M University
cg.researchthemeBiotech and Plant Breeding
cg.researchthemePlant Production and Health
cg.identifier.bibtexciteidTUNCEL:2023
cg.authorship.typesCGIAR and developing country institute
cg.iitasubjectFood Security
cg.iitasubjectFood Systems
cg.iitasubjectPlant Breeding
cg.iitasubjectPlant Production
cg.journalNature Reviews Bioengineering
cg.accessibilitystatusLimited Access
cg.reviewstatusPeer Review
cg.usagerightslicenseCopyrighted; all rights reserved
cg.targetaudienceScientists
cg.identifier.doihttps://doi.org/10.1038/s44222-023-00115-8
cg.iitaauthor.identifierLeena Tripathi: 0000-0001-5723-4981
cg.futureupdate.requiredNo


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