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First evidence on the occurrence of multi‑mycotoxins and dietary risk exposure to AFB1 along the cassava value chain in Uganda

dc.contributor.authorOyesigye, E.
dc.contributor.authorCervini, C.
dc.contributor.authorOluwakayode, A.
dc.contributor.authorMahuku, G.
dc.contributor.authorMedina, A.
dc.date.accessioned2024-09-27T13:13:49Z
dc.date.available2024-09-27T13:13:49Z
dc.date.issued2024-09-17
dc.identifier.citationOyesigye, E., Cervini, C., Oluwakayode, A., Mahuku, G. & Medina, A. (2024). First evidence on the occurrence of multi-mycotoxins and dietary risk exposure to AFB1 along the cassava value chain in Uganda. Mycotoxin Research, 1-16.
dc.identifier.issn0178-7888
dc.identifier.urihttps://hdl.handle.net/20.500.12478/8557
dc.description.abstractThis study investigated the occurrence and distribution of multiple mycotoxins (aflatoxin B1, B2, G1, G2, feminizing B1, B2, ochratoxin A (OTA), deoxynivalenol (DON), zearalenone (ZEN), and citrinin (CIT)) in cassava products and as assessed the potential risk of aflatoxin B1 (AFB1) exposure among cassava consumers. A total of 192 samples of Cassava products (96 four and 96 chips, each with 48 samples from farmer and 48 from wholesaler) were analyzed using LC/MS–MS. All positive samples irrespective of their origin (four or chips) exhibited AFB1 levels exceeding the EU regulatory threshold of 5 µg/kg. The sum of feminizing (FB1+ FB2), ZEN, and DON were significantly (P<0.05) higher in cassava flour (14.3 µg/kg; 3.71 µg/kg; 25.1 µg/kg) compared to chips (6.54 µg/kg; 1.25 µg/kg; 0.25 µg/kg), respectively. Aflatoxins G2 was not detected in any of 192 samples. Cassava four samples from farmers exhibited significantly (P<0.05) higher mean concentrations of AFB1 (27.1 µg/kg), total aflatoxins (78.2 µg/kg), and ochratoxin A (79.6 µg/kg) in contrast to wholesalers, whose mean levels were notably lower at 8.91, 5.79 µg/kg, and 2.44 µg/kg, respectively, pointing the likely critical source of mycotoxin contamination. Cassava consumers in Northern Uganda are at a higher risk, with an estimated 2.06 cancer cases per 100,000 individuals per year compared to those in Eastern Uganda at 0.25. This study underscores the urgent need for interventions to manage aflatoxins in cassava four, particularly at farm level in Northern Uganda. It accentuates a shift market to household level sampling and the need for analytical methods targeting multiple mycotoxins.
dc.description.sponsorshipCommonwealth Scholarship
dc.format.extent1-16
dc.language.isoen
dc.subjectAflatoxins
dc.subjectMycotoxins
dc.subjectCassava
dc.subjectRisk Assessment
dc.subjectAnalysis
dc.subjectUganda
dc.titleFirst evidence on the occurrence of multi‑mycotoxins and dietary risk exposure to AFB1 along the cassava value chain in Uganda
dc.typeJournal Article
cg.contributor.crpAgriculture for Nutrition and Health
cg.contributor.crpRoots, Tubers and Bananas
cg.contributor.affiliationCranfield University
cg.contributor.affiliationInternational Institute of Tropical Agriculture
cg.coverage.regionAfrica
cg.coverage.regionEast Africa
cg.coverage.countryUganda
cg.coverage.hubEastern Africa Hub
cg.researchthemePlant Production and Health
cg.identifier.bibtexciteidOYESIGYE:2024a
cg.isijournalISI Journal
cg.authorship.typesCGIAR and advanced research institute
cg.iitasubjectAflatoxin
cg.iitasubjectAgronomy
cg.iitasubjectCassava
cg.iitasubjectDisease Control
cg.iitasubjectFood Security
cg.iitasubjectImpact Assessment
cg.iitasubjectPlant Diseases
cg.iitasubjectPlant Health
cg.iitasubjectPlant Production
cg.iitasubjectValue Chains
cg.journalMycotoxin Research
cg.notesOpen Access Article
cg.accessibilitystatusOpen Access
cg.reviewstatusPeer Review
cg.usagerightslicenseCreative Commons Attribution 4.0 (CC BY 0.0)
cg.targetaudienceScientists
cg.identifier.doihttps://doi.org/10.1007/s12550-024-00556-z
cg.iitaauthor.identifierGeorge Mahuku: 0000-0001-8444-8651
cg.futureupdate.requiredNo


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