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Mycotoxin exposure in rural residents in northern Nigeria: A pilot study using multiurinary biomarkers

dc.contributor.authorEzekiel, C.N.
dc.contributor.authorWarth, B.
dc.contributor.authorOgara, I.M.
dc.contributor.authorAbia, W.A.
dc.contributor.authorEzekiel, V.C.
dc.contributor.authorAtehnkeng, J.
dc.contributor.authorSulyok, M.
dc.contributor.authorTurner, P.
dc.contributor.authorTayo, G.
dc.contributor.authorKrska, R.
dc.contributor.authorBandyopadhyay, Ranajit
dc.date.accessioned2019-12-04T10:58:26Z
dc.date.available2019-12-04T10:58:26Z
dc.date.issued2014-05
dc.identifier.citationEzekiel, C.N., Warth, B., Ogara, I., Abia, W., Ezekiel, V., Atehnkeng, J., ... & Bandyopadhyay, R. (2014). Mycotoxin exposure in rural residents in northern Nigeria: a pilot study using multi-urinary biomarkers. Environment International, 66, 138-145.
dc.identifier.issn0160-4120
dc.identifier.urihttps://hdl.handle.net/20.500.12478/988
dc.description.abstractA pilot, cross-sectional, correlational study was conducted in eight rural communities in northern Nigeria toinvestigate mycotoxin exposures in 120 volunteers (19 children, 20 adolescents and 81 adults) using a modernLC–MS/MS based multi-biomarker approach. Firstmorning urine samples were analyzed and urinary biomarkerlevels correlated with mycotoxin levels in foods consumed the day before urine collection. A total of eightanalytes were detected in 61/120 (50.8%) of studied urine samples, with ochratoxin A, aflatoxin M1 andfumonisin B1 being the most frequently occurring biomarkers of exposure. These mycotoxin biomarkers werepresent in samples from all age categories, suggestive of chronic (lifetime) exposures. Rough estimates ofmycotoxin intake suggested some exposureswere higher than the tolerable daily intake. Overall, rural consumerpopulations fromNasarawaweremore exposed to severalmixtures ofmycotoxins in their diets relative to thosefromKaduna as shown by food and urine biomarker data. This study has shownthat mycotoxin co-exposuremaybe a major public health challenge in rural Nigeria; this calls for urgent intervention.
dc.format.extent138-145
dc.language.isoen
dc.subjectFood Safety
dc.subjectMycotoxin
dc.titleMycotoxin exposure in rural residents in northern Nigeria: A pilot study using multiurinary biomarkers
dc.typeJournal Article
dc.description.versionPeer Review
cg.contributor.affiliationBabcock University
cg.contributor.affiliationInternational Institute of Tropical Agriculture
cg.contributor.affiliationUniversity of Natural Resources and Life Sciences, Austria
cg.contributor.affiliationNasarawa State University
cg.contributor.affiliationUniversité de Yaoundé I
cg.contributor.affiliationUniversity of Johannesburg
cg.contributor.affiliationUniversity of Maryland
cg.coverage.regionAfrica
cg.coverage.regionWest Africa
cg.coverage.countryNigeria
cg.isijournalISI Journal
cg.authorship.typesCGIAR and developing country institute
cg.iitasubjectAflatoxin
cg.journalEnvironment International
cg.howpublishedFormally Published
cg.accessibilitystatusLimited Access
local.dspaceid77917
cg.identifier.doihttps://dx.doi.org/10.1016/j.envint.2014.02.003


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