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    Seasonal and geographical differences in aflatoxin exposures in Senegal

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    S15ArtWatsonSeasonalInthomDev.pdf (363.0Kb)
    Date
    2015
    Author
    Watson, S.
    Diedhiou, P.M.
    Atehnkeng, J.
    Dem, A.
    Bandyopadhyay, Ranajit
    Srey, C.
    Routledge, M.N.
    Gong, Y.Y.
    Type
    Journal Article
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    Abstract/Description
    The aim of the study was to determine the geographical and seasonal variations in aflatoxin dietary exposure levels in adults from Senegal. A total of 168 adults (50% male) were recruited from three districts: Nioro du Rip (n=90), located in the Sudan Savannah agro-ecological zone where rainfall is sufficient for groundnut growth; Saint-Louis (n=40) and Mboro (n=38), located in the Sahel zone where groundnuts are produced under irrigated conditions. Diet information and samples were collected at groundnut harvest and post-harvest seasons. Plasma aflatoxinalbumin adducts (AF-alb) and total aflatoxin in household groundnut samples were measured by ELISA and a quantitative thin layer chromatography method, respectively. The blood AF-alb geometric mean was 45.7 pg/mg albumin (range 5.5-588.2 pg/mg). Nioro du Rip had a higher AF-alb level at harvest than Saint-Louis and Mboro (80.0 vs 15.6 and 33.3 pg/mg, P<0.001). Similar trends were observed at post-harvest (P<0.05). Seasonal trends were not consistent across the districts as Nioro du Rip had a higher AF-alb level at harvest than post-harvest (80.0 vs 58.6 pg/mg, P=0.026), whereas Saint-Louis had a higher level at post-harvest than harvest (25.6 vs 15.6 pg/mg, P=0.032). It is clear that aflatoxin exposure is prevalent in adults from Senegal and that season and geographical location are strong determinants of aflatoxin exposure.The aim of the study was to determine the geographical and seasonal variations in aflatoxin dietary exposure levels in adults from Senegal. A total of 168 adults (50% male) were recruited from three districts: Nioro du Rip (n=90), located in the Sudan Savannah agro-ecological zone where rainfall is sufficient for groundnut growth; Saint-Louis (n=40) and Mboro (n=38), located in the Sahel zone where groundnuts are produced under irrigated conditions. Diet information and samples were collected at groundnut harvest and post-harvest seasons. Plasma aflatoxinalbumin adducts (AF-alb) and total aflatoxin in household groundnut samples were measured by ELISA and a quantitative thin layer chromatography method, respectively. The blood AF-alb geometric mean was 45.7 pg/mg albumin (range 5.5-588.2 pg/mg). Nioro du Rip had a higher AF-alb level at harvest than Saint-Louis and Mboro (80.0 vs 15.6 and 33.3 pg/mg, P<0.001). Similar trends were observed at post-harvest (P<0.05). Seasonal trends were not consistent across the districts as Nioro du Rip had a higher AF-alb level at harvest than post-harvest (80.0 vs 58.6 pg/mg, P=0.026), whereas Saint-Louis had a higher level at post-harvest than harvest (25.6 vs 15.6 pg/mg, P=0.032). It is clear that aflatoxin exposure is prevalent in adults from Senegal and that season and geographical location are strong determinants of aflatoxin exposure.
    https://dx.doi.org/10.3920/WMJ2014.1824
    Multi standard citation
    Permanent link to this item
    https://hdl.handle.net/20.500.12478/877
    Digital Object Identifier (DOI)
    https://dx.doi.org/10.3920/WMJ2014.1824
    IITA Subjects
    Aflatoxin
    Agrovoc Terms
    Aflatoxins; Groundnuts; Aspergillus Aflatoxin; Groundnuts; Aspergillus Aflatoxin; Groundnuts; Aspergillus Aflatoxin; Groundnuts; Aspergillus
    Regions
    Africa; West Africa
    Countries
    Nigeria
    Journals
    World Mycotoxin Journal World Mycotoxin Journal
    Collections
    • Journal and Journal Articles4835

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