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Seasonal and geographical differences in aflatoxin exposures in Senegal

dc.contributor.authorWatson, S.
dc.contributor.authorDiedhiou, P.M.
dc.contributor.authorAtehnkeng, J.
dc.contributor.authorDem, A.
dc.contributor.authorBandyopadhyay, Ranajit
dc.contributor.authorSrey, C.
dc.contributor.authorRoutledge, M.N.
dc.contributor.authorGong, Y.Y.
dc.date.accessioned2019-12-04T10:57:56Z
dc.date.available2019-12-04T10:57:56Z
dc.date.issued2015
dc.identifier.citationWatson, S., Diedhiou, P.M., Atehnkeng, J., Dem, A., Bandyopadhyay, R., Srey, C., ... & Gong, Y.Y. (2015). Seasonal and geographical differences in aflatoxin exposures in Senegal. World Mycotoxin Journal, 1-8.
dc.identifier.issn1875-0710
dc.identifier.urihttps://hdl.handle.net/20.500.12478/877
dc.descriptionArticle in Press
dc.description.abstractThe aim of the study was to determine the geographical and seasonal variations in aflatoxin dietary exposure levels in adults from Senegal. A total of 168 adults (50% male) were recruited from three districts: Nioro du Rip (n=90), located in the Sudan Savannah agro-ecological zone where rainfall is sufficient for groundnut growth; Saint-Louis (n=40) and Mboro (n=38), located in the Sahel zone where groundnuts are produced under irrigated conditions. Diet information and samples were collected at groundnut harvest and post-harvest seasons. Plasma aflatoxinalbumin adducts (AF-alb) and total aflatoxin in household groundnut samples were measured by ELISA and a quantitative thin layer chromatography method, respectively. The blood AF-alb geometric mean was 45.7 pg/mg albumin (range 5.5-588.2 pg/mg). Nioro du Rip had a higher AF-alb level at harvest than Saint-Louis and Mboro (80.0 vs 15.6 and 33.3 pg/mg, P<0.001). Similar trends were observed at post-harvest (P<0.05). Seasonal trends were not consistent across the districts as Nioro du Rip had a higher AF-alb level at harvest than post-harvest (80.0 vs 58.6 pg/mg, P=0.026), whereas Saint-Louis had a higher level at post-harvest than harvest (25.6 vs 15.6 pg/mg, P=0.032). It is clear that aflatoxin exposure is prevalent in adults from Senegal and that season and geographical location are strong determinants of aflatoxin exposure.The aim of the study was to determine the geographical and seasonal variations in aflatoxin dietary exposure levels in adults from Senegal. A total of 168 adults (50% male) were recruited from three districts: Nioro du Rip (n=90), located in the Sudan Savannah agro-ecological zone where rainfall is sufficient for groundnut growth; Saint-Louis (n=40) and Mboro (n=38), located in the Sahel zone where groundnuts are produced under irrigated conditions. Diet information and samples were collected at groundnut harvest and post-harvest seasons. Plasma aflatoxinalbumin adducts (AF-alb) and total aflatoxin in household groundnut samples were measured by ELISA and a quantitative thin layer chromatography method, respectively. The blood AF-alb geometric mean was 45.7 pg/mg albumin (range 5.5-588.2 pg/mg). Nioro du Rip had a higher AF-alb level at harvest than Saint-Louis and Mboro (80.0 vs 15.6 and 33.3 pg/mg, P<0.001). Similar trends were observed at post-harvest (P<0.05). Seasonal trends were not consistent across the districts as Nioro du Rip had a higher AF-alb level at harvest than post-harvest (80.0 vs 58.6 pg/mg, P=0.026), whereas Saint-Louis had a higher level at post-harvest than harvest (25.6 vs 15.6 pg/mg, P=0.032). It is clear that aflatoxin exposure is prevalent in adults from Senegal and that season and geographical location are strong determinants of aflatoxin exposure.
dc.language.isoen
dc.subjectAflatoxins
dc.subjectGroundnuts
dc.subjectAspergillus Aflatoxin
dc.subjectGroundnuts
dc.subjectAspergillus Aflatoxin
dc.subjectGroundnuts
dc.subjectAspergillus Aflatoxin
dc.subjectGroundnuts
dc.subjectAspergillus
dc.titleSeasonal and geographical differences in aflatoxin exposures in Senegal
dc.typeJournal Article
dc.description.versionPeer Review
cg.contributor.affiliationQueen's University Belfast
cg.contributor.affiliationGaston Berger University
cg.contributor.affiliationInternational Institute of Tropical Agriculture
cg.contributor.affiliationUniversity of Leeds
cg.contributor.affiliationUniversité Cheikh Anta Diop
cg.coverage.regionAfrica
cg.coverage.regionWest Africa
cg.coverage.countryNigeria
cg.isijournalISI Journal
cg.authorship.typesCGIAR and developing country institute
cg.iitasubjectAflatoxin
cg.journalWorld Mycotoxin Journal World Mycotoxin Journal
cg.howpublishedFormally Published
cg.accessibilitystatusLimited Access
local.dspaceid76376
cg.identifier.doihttps://dx.doi.org/10.3920/WMJ2014.1824


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